The Happening 2008

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When a deadly airborne virus threatens to wipe out the northeastern United States, teacher Elliott Moore (Mark Wahlberg) and his wife (Zooey Deschanel) flee from contaminated cities into the countryside in a fight to discover the truth. Is it terrorism, the accidental release of some toxic military bio weapon -- or something even more sinister? John Leguizamo and Betty Buckley co-star in this thriller from writer-director M. Night Shyamalan.

Director: M. Night Shyamalan
Top cast: Mark Wahlberg, Zooey Deschanel, John Leguizamo, Spencer Breslin, Betty Buckley
More details at Entora.com
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Best apocalyptic / end of the world movies
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End of the world, pre or post-apocalyptic environments, viral infection disasters